Organometallic Compounds
Medchemexpress LLC OSI-930 | 728033-96-3 | MFCD11100358 | 98.3% | 443.44 | C22H16F3N3O2S | 10 MG
OSI-930 is a small-molecule tyrosine kinase inhibitor selective for c-Kit, KDR (VEGFR2), and CSF-1R (c-Fms), provided as a solid for research use. It exhibits in vitro potency with reported IC50s of ~80 nM (Kit), 9 nM (KDR), and 15 nM (CSF-1R) and has shown antitumor activity in preclinical models.
- Selective inhibition of c-Kit, KDR, and CSF-1R.
- Low nanomolar potency against VEGFR2 (KDR).
- Useful for kinase inhibition and cancer biology research.
- High listed purity (≈98.3%).
- Supplied as a solid in small-scale quantities suitable for laboratory studies.
eMolecules 4-(TERT-BUTYLDIMETHYLSILYLOXY) CYCLOHEXANAMINE | 121936-51-4 | MFCD18206131 | 1g
AstaTech | 4-(TERT-BUTYLDIMETHYLSILYLOXY) CYCLOHEXANAMINE | 1g | 273176308 | AB10752 | 95.000 | 121936-51-4 | MFCD18206131 | 229.439 | C12H27NOSi
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Medchemexpress LLC Tri(Amino-PEG3-amide)-amine | 2523025-40-1 | 98.0% | C33H69N7O12 | 50 MG
Tri(Amino-PEG3-amide)-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- For research use only.
Apexbio Technology LLC Epidermal growth factor receptor (994-1002) acetyl/amide 25mg
Epidermal growth factor receptor 994-1002 acetyl amide is a peptide fragment derived from the epidermal growth factor receptor (EGFR) acetylated and amidated at its termini It is designed to serve as a tool for investigating receptor-ligand interactions and receptor activation mechanisms associated with EGFR-mediated signaling pathways Epidermal growth factor receptor 994-1002 acetyl amide acts by enabling the study of EGFR activation particularly receptor dimerization and autophosphorylation processes Based on its biological characteristics this peptide has research potential in evaluating therapeutic strategies targeting EGFR-mediated oncogenesis including studies of proliferation differentiation migration and survival in malignancies such as glioblastoma and lung cancers
Apexbio Technology LLC OSI-930 728033-96-3 10mM (in 1mL DMSO)
OSI-930 (CAS 728033-96-3) is a small molecule inhibitor targeting multiple receptor tyrosine kinases including Flt1 (IC 8 nM) KDR/VEGFR2 (IC 9 nM) CSF-1R (IC 15 nM) Lck c-Raf and Kit (IC 80 nM) In cellular studies OSI-930 inhibits proliferation and induces apoptosis in HMC-1 cells whose survival is dependent on Kit signaling while exhibiting minimal effects on COLO-205 cells under standard conditions Additionally OSI-930 inactivates cytochrome P450 3A4 in a time- and concentration-dependent manner and alters its spectral properties These characteristics make OSI-930 a valuable tool compound for investigating receptor tyrosine kinase signaling pathways and related cellular processes in cancer research
eMolecules Synthonix - Stock 3-tert-Butyldimethylsilyloxypropanal 250mg 495873820 B64752 0 000 89922-82-7 MFCD04039464 188 342 C9H20O2Si
Synthonix - Stock 3-tert-Butyldimethylsilyloxypropanal 250mg 495873820 B64752 0 000 89922-82-7 MFCD04039464 188 342 C9H20O2Si
eMolecules 5-(tert-Butyldimethylsilyloxy)-2-fluorobenzaldehyde | 113984-67-1 | MFCD17676576 | 1g
Apollo Scientific | 5-(tert-Butyldimethylsilyloxy)-2-fluorobenzaldehyde | 1g | 562442068 | PC400031 | | 113984-67-1 | MFCD17676576 | 254.376 | C13H19FO2Si
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Medchemexpress LLC Eg00229 trifluoroacetate | 1210945-69-9 | 98.0% | 611.60 | C19H20F3N7O7S3 | 100 MG
EG00229 trifluoroacetate is a small-molecule neuropilin-1 (NRP1) receptor antagonist supplied for research use. It selectively inhibits VEGF-A binding to the NRP1 b1 domain and is intended for in vitro and preclinical studies of NRP1-mediated signaling.
- Neuropilin-1 receptor antagonist that blocks VEGF-A binding.
- Reported IC50 ≈3 μM against purified NRP1 b1 domain and ≈8 μM in cell binding assays.
- Trifluoroacetate salt form for consistent formulation.
- High purity (≈98.0%).
- Molecular weight 611.6, suitable for biochemical and binding assays.
- Intended for research use in mechanistic and signaling studies.
eMolecules 1-(3-BROMOPROPOXY)-4-CHLOROBENZENE | 27983-04-6 | MFCD00596632 | 1g
AstaTech | 1-(3-BROMOPROPOXY)-4-CHLOROBENZENE | 1g | 384829480 | 20619 | 95.000 | 27983-04-6 | MFCD00596632 | 249.530 | C9H10BrClO
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Medchemexpress LLC 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-collidine | 632-93-9 | MFCD00005950 | >98.0% | 267.33 g·mol⁻¹ | C14H21NO4 | 1 G
Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate (CAS 632-93-9) is a diethoxycarbonyl-substituted dihydropyridine used as a research reagent that interferes with heme synthesis and is employed in studies of porphyrin metabolism and ferrochelatase activity.
- High purity: >98.0% (GC).
- Chemical formula C14H21NO4; molecular weight 267.33 g·mol⁻¹.
- Available in gram-scale quantities (1 G, 5 G, 25 G).
- Used as a biochemical tool to block heme synthesis in cellular and in vivo studies.
- Solid with reported melting point 130-132 °C for handling and storage considerations.
Pfaltz & Bauer Octadecyldimethylmethoxysilane 25G | 71808-65-6
Octadecyldimethylmethoxysilane 25G | 71808-65-6
eMolecules 1-(Triisopropylsilyl)-1-propyne | 82192-57-2 | MFCD00015636 | 25g
Combi-Blocks | 1-(Triisopropylsilyl)-1-propyne | 25g | 517032047 | QC-3936 | 98.000 | 82192-57-2 | MFCD00015636 | 196.409 | C12H24Si
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